[The problem of pharmacoresistant tremor in Parkinson's disease and essential tremor].

Authors: Titova NV, Katunina EA, Tairova RT, Sen'ko IV, Dzhafarov VM, Malykhina EA

MR-guided focused ultrasound (MRg-FUS) is a new noninvasive method for the treatment of contralateral disabling and pharmacoresistant tremor. Clinical studies have confirmed the high efficacy and safety of using MRg-FUS in patients with essential tremor and Parkinson's disease, in short and long-term studies. Advantages of this method in comparison with currently used invasive and noninvasive technics, potential brain target areas, the possibility of bilateral intervention, indications and contraindications are discussed.

Introduction

Purpose Other

Study Objective To review and analyze the problem of pharmacoresistant tremor in Parkinson's disease and essential tremor.

Disease model Parkinson's disease; essential tremor

Outcomes and Safety

Summary of Outcomes This paper reviews the clinical problem of pharmacoresistant tremor in Parkinson's disease and essential tremor and highlights the need for alternative (often surgical or device-based) therapies; no focused ultrasound parameters or experimental outcomes are reported.

Safety-related matter The provided text contains no mention of safety issues or adverse effects.

Brain Region

Visualization unavailable

Ultrasound Parameters

Focal Characteristics focal depth: None, focal length: None, aperture size: None

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