Image-Guided, Asleep Deep Brain Stimulation.
Authors: Ko AL, Burchiel KJ
Deep brain stimulation (DBS) has become an established treatment for medically refractory movement disorders including Parkinson's disease, essential tremor, and dystonia. The field of DBS continues to evolve with advances in patient selection, target identification, electrode and pulse generator technology, and the development of more effective stimulation paradigms such as closed-loop stimulation. Furthermore, as the safety and efficacy of DBS improves through better hardware design and deeper understanding of its mechanisms of action, the indications for DBS will continue to expand to cover a wider range of disorders. Finally, the recent approval of MR-guided focused ultrasound for the treatment of essential tremor and potentially other movement disorders heralds a resurgence in lesion creation as a viable alternative to DBS for selected patients.
Introduction
Purpose
Other
Study Objective
To evaluate the feasibility, accuracy, and clinical outcomes of image-guided deep brain stimulation performed while patients are asleep (under general anesthesia).
Outcomes and Safety
Summary of Outcomes
No experimental results or outcomes are provided in the supplied text, so no biological or behavioral effects can be summarized; no focused ultrasound parameters were reported.
Safety-related matter
The provided text contains only the title and includes no mention of safety, adverse effects, or related findings.
Brain Region
Ultrasound Parameters
Focal Characteristics
Focal depth: None; Focal length: None; Aperture size: None
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