High-intensity focused ultrasound for noninvasive functional neurosurgery.
Authors: Martin E, Jeanmonod D, Morel A, Zadicario E, Werner B
Transcranial magnetic resonance (MR)-guided high-intensity focused ultrasound (tcMRgHIFU) implies a novel, noninvasive treatment strategy for various brain diseases. Nine patients with chronic neuropathic pain were treated with selective medial thalamotomies. Precisely located thermal ablations of 4mm in diameter were produced at peak temperatures of 51 degrees C to 60 degrees C under continuous visual MR guidance and MR thermometry. The resulting lesions are clearly visible on follow-up MR imaging. All treatments were well tolerated, without side effects or neurological deficits. This is the first report on successful clinical application of tcMRgHIFU in functional brain disorders, portraying it as safe and reliable for noninvasive neurosurgical interventions.
Introduction
Purpose
Thermal ablation
Study Objective
To evaluate the use of high-intensity focused ultrasound as a noninvasive technique for performing functional neurosurgery.
Outcomes and Safety
Summary of Outcomes
Only the paper title was provided; no experimental details, biological/behavioral outcomes, or focused ultrasound parameters are available in the supplied text to summarize.
Safety-related matter
No safety or adverse effects were mentioned in the provided text.
Brain Region
Ultrasound Parameters
Focal Characteristics
Focal depth: None; Focal length: None; Aperture size: None
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