[MR-guided focused ultrasound. Current and future applications].
Authors: Trumm CG, Napoli A, Peller M, Clevert DA, Stahl R, Reiser M, Matzko M
High-intensity focused ultrasound (synonyms FUS and HIFU) under magnetic resonance imaging (MRI) guidance (synonyms MRgFUS and MR-HIFU) is a completely non-invasive technology for accurate thermal ablation of a target tissue while neighboring tissues and organs are preserved. The combination of FUS with MRI for planning, (near) real-time monitoring and outcome assessment of treatment markedly enhances the safety of the procedure. The MRgFUS procedure is clinically established in particular for the treatment of symptomatic uterine fibroids, followed by palliative ablation of painful bone metastases. Furthermore, promising results have been shown for the treatment of adenomyosis, malignant tumors of the prostate, breast and liver and for various intracranial applications, such as thermal ablation of brain tumors, functional neurosurgery and transient disruption of the blood-brain barrier.
Introduction
Purpose
Thermal ablation
Study Objective
To review the current clinical and research applications and potential future uses of MR-guided focused ultrasound.
MRI or image guidance method
MR-guided (MRI)
Outcomes and Safety
Summary of Outcomes
Only the paper title was provided; no experimental results, biological or behavioral effects, or specific focused ultrasound parameters are reported in the supplied text.
Safety-related matter
No safety-related information or adverse effects are mentioned in the provided text; only the article title is present.
Brain Region
Ultrasound Parameters
Focal Characteristics
Focal depth: None; Focal length: None; Aperture size: None
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