Multimodality intraoperative MRI for brain tumor surgery.
Authors: Colen RR, Kekhia H, Jolesz FA
Intraoperative MRI has already fundamentally changed the way current brain tumor surgery is performed. The ability to integrate high-field MRI into the operating room has allowed intraoperative MRI to emerge as an important adjunct to CNS tumor treatment. Furthermore, the ability of MRI to successfully couple with molecular imaging (PET and/or optical imaging), neuroendoscopy and therapeutic devices, such as focused ultrasound, will allow it to emerge as an important image-guidance modality for improving brain tumor therapy and outcomes.
Introduction
Purpose
Other
Study Objective
To evaluate the utility of multimodality intraoperative MRI during brain tumor surgery.
Animal model / Human subject
Not specified in provided text
Disease model
brain tumor
MRI or image guidance method
MRI
Targeted brain region(s)
Tumor
Target coordinates
Not provided
Cargo name and characteristics
Not specified in the provided text.
Route of administration
not specified in provided text
Outcomes and Safety
Summary of Outcomes
No biological or behavioral effects are reported in the provided text, and no focused ultrasound parameters were tested or described.
Duration of biological effect
not provided
Safety-related matter
No safety concerns or adverse effects are mentioned in the provided text.
Brain Region
Ultrasound Parameters
Ultrasound instrument
Not provided
FUS Frequency
Not provided
FUS Intensity
Not provided
FUS Pressure
Not provided
FUS Mode
Not provided
Pulse duration
Not provided
Duration of a single FUS session
Not provided
Focal Characteristics
Not provided
Treatment frequency
single
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