Current and Emerging Treatments of Essential Tremor.
Authors: Ondo WG
Established medications that improve tremor include beta-adrenergic antagonists, primidone, topiramate, and ethanol. Less consistent efficacy is reported with many other medications, usually antiepileptic drugs. A number of investigational medications, including T-type calcium channel blockers and allosteric gamma-aminobutyric acid-A modulators, are being developed for tremor. Deep brain stimulation techniques continues to be refined and focused ultrasound thalamotomy now offers an incisionless surgical option. Finally a number of peripheral electrical and mechanical devices are under development for tremor.
Introduction
Purpose
Thermal ablation
Study Objective
To review and summarize current and emerging treatments for essential tremor.
Disease model
Essential Tremor
Targeted brain region(s)
Thalamus
Outcomes and Safety
Summary of Outcomes
No experimental biological or behavioral outcomes or focused ultrasound parameters are reported in the provided text.
Safety-related matter
No safety issues or adverse effects are mentioned in the provided text.
Brain Region
Ultrasound Parameters
Focal Characteristics
focal depth: None; focal length: None; aperture size: None
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