DESIGN AND FABRICATION OF A FOCUSED ULTRASOUND DEVICE FOR MINIMALLY-INVASIVE NEUROSURGERY: REPORTING A SECOND, MINIATURIZED AND MR-COMPATIBLE PROTOTYPE WITH STEERING CAPABILITIES.

Authors: Acord M, Kaovasia TP, Gamo NJ, Xiong T, Morrison K, Tyler B, Luciano M, Manbachi A

Many surgeons are faced with inoperable or only partially operable brain lesions, such as tumors. Even when surgery is feasible, patient outcome is greatly affected by blood loss or infection. This has led many physicians toward non- or minimally-invasive surgery, which demands specialized toolkits. Focused ultrasound has great potential for assisting in such procedures due to its ability to focus a few cm away from the surface of the transducer. In a prior study, we developed a focused ultrasound prototype that could fit within a BrainPath trocar, specifically made for minimally invasive brain surgery. Here, we present the design and fabrication of a second prototype that reduces size, is MR-compatible, and has electronic steering capabilities.

Introduction

Purpose Thermal ablation

Study Objective To design and fabricate a second focused ultrasound prototype for minimally invasive brain surgery that is reduced in size, MR-compatible, and features electronic steering.

Disease model brain tumor

Outcomes and Safety

Summary of Outcomes No biological or behavioral effects were reported; the paper describes a second focused ultrasound prototype that is reduced in size, MR-compatible, and has electronic steering capabilities, and it did not report testing of specific ultrasound parameters.

Safety-related matter No safety issues or adverse effects are mentioned in the provided text.

Brain Region

Visualization unavailable

Ultrasound Parameters

Focal Characteristics Focal depth: None; Focal length: None; Aperture size: None

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