Reply to Letter from Price et al, re: Translation of focused ultrasound for blood-brain barrier opening in glioma.
Authors: Brighi C, Salimova E, de Veer M, Puttick S, Egan G
No abstract available
Introduction
Purpose
Drug delivery with BBB opening
Study Objective
To respond to Price et al.'s letter regarding the translation of focused ultrasound for opening the blood-brain barrier in glioma.
Disease model
glioma
Targeted brain region(s)
Blood-Brain Barrier
Cargo name and characteristics
No therapeutic or experimental cargo specified in the provided text. The title references focused ultrasound-mediated blood–brain barrier opening in glioma (a physical modality), but no AAV, protein, small molecule, nanoparticle, or other cargo is named.
Outcomes and Safety
Summary of Outcomes
Focused ultrasound can transiently open the blood–brain barrier in glioma, potentially enabling enhanced delivery of therapeutics.
Safety-related matter
The provided text contains no mention of safety issues or adverse effects.
Brain Region
Ultrasound Parameters
Ultrasound instrument
None.
FUS Mode
unknown
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