Ultrasound Neuromodulation as a New Brain Therapy.
Authors: Beisteiner R, Hallett M, Lozano AM
Within the last decade, ultrasound has been "rediscovered" as a technique for brain therapies. Modern technologies allow focusing ultrasound through the human skull for highly focal tissue ablation, clinical neuromodulatory brain stimulation, and targeted focal blood-brain-barrier opening. This article gives an overview on the state-of-the-art of the most recent application: ultrasound neuromodulation as a new brain therapy. Although research centers have existed for decades, the first treatment centers were not established until 2020, and clinical applications are spreading rapidly.
Introduction
Purpose
Transcranial ultrasound stimulation
Study Objective
To provide a state-of-the-art overview of ultrasound neuromodulation as a new noninvasive brain therapy, summarizing clinically applicable technologies, current therapeutic results, and its benefits compared with electromagnetic therapies.
Outcomes and Safety
Summary of Outcomes
Focused ultrasound enables highly focal tissue ablation, clinical neuromodulatory brain stimulation, and targeted focal blood–brain barrier opening. This paper is a state-of-the-art overview and does not report specific tested ultrasound parameter sets or list particular parameter values as successful.
Safety-related matter
The provided text does not mention any safety concerns or adverse effects related to ultrasound neuromodulation.
Brain Region
Ultrasound Parameters
Focal Characteristics
Focal depth: None; Focal length: None; Aperture size: None
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