MR Thermometry during Transcranial MR Imaging-Guided Focused Ultrasound Procedures: A Review.

Interest in transcranial MR imaging-guided focused ultrasound procedures has recently grown. These incisionless procedures enable precise focal ablation of brain tissue using real-time monitoring by MR thermometry. This article will provide an updated review on clinically applicable technical underpinnings and considerations of proton resonance frequency MR thermometry, the most common clinically used MR thermometry sequence.

Introduction

Purpose Thermal ablation

Study Objective To provide an updated review of clinically applicable considerations, pitfalls, and limitations of proton resonance frequency MR thermometry for safe and effective transcranial MR-guided focused ultrasound procedures.

MRI or image guidance method MR imaging–guided (real-time proton resonance frequency MR thermometry)

Outcomes and Safety

Summary of Outcomes Transcranial MR-guided focused ultrasound enables precise, incisionless focal ablation of brain tissue with real-time monitoring using proton-resonance-frequency MR thermometry; the review outlines clinically relevant technical considerations, pitfalls, and limitations to achieve controlled treatments and avoid complications. The paper did not test or report specific focused ultrasound parameter sets as successful.

Safety-related matter The article discusses safety considerations, pitfalls, and limitations of proton resonance frequency MR thermometry to avoid complications during MRgFUS procedures; no specific adverse effects are reported.

Brain Region

Visualization unavailable

Ultrasound Parameters

Focal Characteristics Focal depth: None; Focal length: None; Aperture size: None

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