[An experimental study of stereotaxic destruction on the cat brain by intense focused ultrasound. The improvement of the apparatus for experiment].
Authors: Ishii M
No abstract available
Introduction
Purpose
Thermal ablation
Study Objective
To experimentally evaluate stereotaxic destruction of the cat brain using intense focused ultrasound and to improve the experimental apparatus.
Animal model / Human subject
cat, domestic, adult, not reported
Disease model
healthy
Targeted brain region(s)
Thalamus
Outcomes and Safety
Summary of Outcomes
A stereotaxic intense FUS system produced highly localized destructive lesions in the cat brain, demonstrating precise spatial control for functional neurosurgery
Safety-related matter
The system enabled precise lesioning with minimal damage to intervening tissues; however, precise alignment and cooling were required to avoid non-target thermal injury.
Brain Region
Ultrasound Parameters
Ultrasound instrument
multibeam focused ultrasound system with stereotaxic frame
FUS Frequency
1.0 MHz
Duration of a single FUS session
0.5–2.0 s
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