[An experimental study of stereotaxic destruction on the cat brain by intense focused ultrasound. The improvement of the apparatus for experiment].
Authors: Ishii M
No abstract available
Introduction
Purpose
Thermal ablation
Study Objective
To experimentally evaluate stereotaxic destruction of the cat brain using intense focused ultrasound and to improve the experimental apparatus.
Animal model / Human subject
cat, domestic, adult, not reported
Disease model
healthy
Targeted brain region(s)
Thalamus
Outcomes and Safety
Summary of Outcomes
A stereotaxic intense FUS system produced highly localized destructive lesions in the cat brain, demonstrating precise spatial control for functional neurosurgery
Duration of biological effect
not reported
Safety-related matter
The system enabled precise lesioning with minimal damage to intervening tissues; however, precise alignment and cooling were required to avoid non-target thermal injury.
Brain Region
Ultrasound Parameters
Ultrasound instrument
multibeam focused ultrasound system with stereotaxic frame
FUS Frequency
1.0 MHz
FUS Intensity
not reported
FUS Pressure
not reported
FUS Mode
not reported
Pulse duration
not reported
Duration of a single FUS session
0.5–2.0 s
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