Focused ultrasound: a Trojan horse to deliver chemotherapeutics across blood-tumor barrier.
Authors: Rehman G, Shafiq MM, Qadri HM, Khan ZM, Bashir A
No abstract available
Introduction
Purpose
other
Study Objective
To evaluate focused ultrasound as a method to enhance delivery of chemotherapeutic drugs across the blood-tumor barrier.
Animal model / Human subject
Not specified in the provided text.
Disease model
glioma
MRI or image guidance method
Not specified in the provided text
Targeted brain region(s)
Not Specified
Cargo name and characteristics
Not specified in the provided text
Route of administration
Not applicable (no drug or cargo administered)
Outcomes and Safety
Summary of Outcomes
Focused ultrasound transiently opens the blood-tumor barrier to enhance delivery and uptake of chemotherapeutic agents into tumors.
Duration of biological effect
Not reported
Safety-related matter
No safety issues or adverse effects are mentioned in the provided text.
Brain Region
Ultrasound Parameters
FUS Frequency
not specified
FUS Intensity
Not reported in provided text
FUS Pressure
Not reported in provided text
FUS Mode
not specified
Pulse duration
Not reported
Duration of a single FUS session
Not reported in the provided text.
Focal Characteristics
Not specified
Treatment frequency
Not specified
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