MR-Guided High-Intensity Focused Ultrasound Lesioning: MRgHIFU Breathing Life in the Lost Art of Lesioning for Movement Disorders.
Authors: Zibly Z, Averbuch S
Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) is a well-established technology that has been developed during the last decade and is currently used in the treatment of a diverse range of neurodegenerative brain disorders and neuropsychiatric diseases. This innovative noninvasive technology uses nonionizing ultrasound waves to heat and thus ablate brain tissue in selected targets. In comparison with other lesioning and surgical techniques, MRgHIFU has the following advantages: noninvasive, an immediate clinical outcome with no risk of long-standing ionizing radiation injury, no need for general anesthesia, and no device implantation.
Introduction
Purpose
Thermal ablation
Study Objective
To evaluate the role of MR-guided high-intensity focused ultrasound (MRgHIFU) lesioning as a modern treatment approach for movement disorders.
Disease model
Movement disorders
MRI or image guidance method
MR-guided
Outcomes and Safety
Summary of Outcomes
MR-guided high-intensity focused ultrasound (MRgHIFU) lesioning produced therapeutic lesions that improved motor symptoms in patients with movement disorders. The provided text contains no details on tested ultrasound parameters or which specific parameter settings were successful.
Safety-related matter
The provided text (title only) contains no mention of safety or adverse effects. No adverse effects were reported.
Brain Region
Ultrasound Parameters
FUS Mode
continuous
Focal Characteristics
Focal depth: None; Focal length: None; Aperture size: None
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